On the other hand, the Saints are fresh off a dominating 24-6 win against the New York Giants, with Derek Carr shining with 3 touchdowns and no interceptions. On the defensive side, the Saints have been more successful against the pass, ranking 6th in the league in opponent passing yards per game, and they will look to capitalize on this strength in their matchup against the Rams.

The Saints, who rank 25th against the run this season, will have their work cut out for them in containing Williams and the Rams’ potent ground game. The return of Cooper Kupp from injury has bolstered the Rams’ offense, and the emergence of Kyren Williams as a formidable running threat has added another dimension to their game.

The Rams are coming off a solid 28-20 win against the Washington Commanders, with QB Matt Stafford leading the charge with 258 yards passing and two touchdowns. The moneyline opened at +164 for the Saints and -198 for the Rams, indicating the confidence that oddsmakers have in the Rams’ ability to come out on top in this matchup. The Rams opened as four point favorites at DraftKings Sportsbook, with the over/under total set at 44.5. As usual, the game will broadcast on Amazon Prime TV at 8:15 pm ET, and should be the first of several great games over the course of week 16s matchups. With both teams entering the matchup with a record of 7-7, the stakes are high as they compete for a playoff spot. The New Orleans Saints and the Los Angeles Rams are set to face off in what promises to be an intense, must win game for both sides on Thursday Night Football.

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